Gran Colombian cities are cities that can be founded by the Gran Colombian civilization in Civilization VI and its expansions. The first city founded is the 
Capital, and the names of future cities are chosen at random from the list below.
The names listed are default names; players can change their cities' names if they choose.
List of cities[]
| City Name | Notes |
|---|---|
| Capital
| |
| Bogotá | Formerly known as Santa Fe de Bogotá; capital of and largest city in present-day Colombia, founded in 1538 |
| Cities | |
| Caracas | Present-day capital and largest city of Venezuela, founded in 1567 |
| Quito | Present-day capital and largest city of Ecuador, founded in 1534 |
| Guayaquil | Second largest city and capital of the Guayas province in Ecuador; capital of the independent Free State of Guayaquil, founded in 1535 |
| Maracaibo | Second largest city and capital of the Zulia state in Venezuela, founded in 1529 |
| Cartagena de Indias | Capital of the Bolivar department in Colombia and a key port during the colonial era, founded in 1533 |
| Panamá | Present-day capital and largest city of Panamá, founded in 1519 |
| Popayán | Capital of the Cauca department in Colombia, founded in 1537 |
| Cuenca | Third largest city and capital of the Azuay province in Ecuador, founded in 1557 |
| Cumaná | Capital of the Sucre state in Venezuela and the oldest continuously inhabited, European-established settlement in the continent, founded in 1515 |
| Barinas | Capital of the Barinas state in Venezuela, founded in 1577 |
| Cali | Third largest city and capital of the Valle del Cauca department in Colombia, also known as Santiago de Cali, founded in 1536 |
| Valencia de Carabobo | Third largest city and capital of the Carabobo state in Venezuela, also known simply as Valencia, founded in 1555 |
| Santa Marta | Capital of the Magdalena department and oldest continuously inhabited Spanish settlement in modern-day Colombia, founded in 1525 |
| Loja | Capital of the Loja province in Ecuador, founded in 1548 |
| Angostura | Capital of the Bolivar state in Venezuela; its present-day name is Ciudad Bolivar, founded in 1545 |
| Pasto | Capital of the Nariño department in Colombia, founded in 1537 |
| Nueva Barcelona | Capital of the Anzoátegui State in Venezuela; its true name is Barcelona, but its named in-game Nueva Barcelona to avoid confusion with the Spanish city, founded in 1638 |
| Neiva | Capital of the Huila department in Colombia; capital of the Spanish Province of Neiva, founded in 1612 |
| Mérida | Capital of the Mérida state in Venezuela, founded in 1558 |
| Portoviejo | Capital of the Manabí province in Ecuador, founded in 1535 |
| Riobamba | Capital of the Chimborazo province in Ecuador, founded in 1575 |
| Ibarra | Capital of the Imbabura province in Ecuador, founded in 1606 |
| Riohacha | Capital of the La Guajira department in Colombia, founded in 1545 |
| Quibdó | Capital of the Chocó department in Colombia, founded in 1664 |
| Nueva Pamplona | Town in the Norte de Santander department in northeastern Colombia; its true name is Pamplona, but its named in-game Nueva Pamplona to avoid confusion with the Spanish city; capital of the Spanish colonial Province of Pamplona, founded in 1549 |
| Santiago de Veraguas | Capital of the Veraguas province in Panama, founded in 1621 |
| La Asunción | Capital of the Nueva Esparta state in Venezuela, founded in 1562 |
| Achaguas | Town in the Apure State in Western Venezuela, founded in 1774 |
| Honda | Town in the Tolima department in Central Colombia; port of entrance to Bogotá from the Magdalena River and from the Caribbean, founded in 1539 |
| Socorro | Town in the Santander Department in northeastern Colombia; capital of the Spanish Province of Socorro, founded in 1683 |
| Mompós | Town in the Bolívar Department in northern Colombia; inland port to defend ships from pirates, founded in 1537 |
| Trujillo | Capital of the Trujillo state in Venezuela, founded in 1557 |
| Santa Fe de Antioquia | Town in the Antioquia department in Northwest Colombia; capital of the independent Free State of Antioquia, founded in 1541 |
| Pore | Town in Department of Casanare in Eastern Colombia; capital of the Spanish Province of Casanare; a gathering spot for Bolívar's armies before capturing Bogotá, founded in 1644 |
| Cúcuta | Capital of the Norte de Santader department in Colombia, at the Venezuelan border; known for its military history and for the Congress of Cúcuta, founded in 1733 |
| Mariquita | Town in the Tolima department in Central Colombia; former capital of the Spanish Province of Mariquita and seat of the Royal Botanical Expedition, founded in 1551 |
| San Fernando de Apure | Capital of the Apure State in Venezuela, founded in 1788 |
| Medellín | Second largest city and capital of the Antioquia department in Colombia, founded in 1616 |
| Barquisimeto | Capital of the Lara state in Venezuela, founded in 1552 |