The Missile Cruiser is an Information Era naval ranged unit in Civilization VI. It upgrades from the Battleship (or its replacements).
In the Gathering Storm expansion, the Missile Cruiser requires 1 
Oil to train and 1 Oil per turn to maintain.
Strategy
The Missile Cruiser is the strongest ship in your modern navy, armed with advanced surface-to-air and surface-to-surface missiles, torpedoes, and everything else the modern ranged weaponry is able to supply. Besides its great ranged strength, long range and very decent melee strength, it is terrifyingly effective when intercepting enemy aircraft! When acting in conjunction with Destroyers to detect and attack enemy Submarines and Nuclear Submarines, the Missile Cruiser is able to provide full cover for your fleets. Not only that, but it is able to lay effective siege to cities, since its weapons do full damage against city defenses!
But the best part is that the Missile Cruiser doesn't require resources (in vanilla Civilization VI and Rise and Fall), which means that whatever problems you had acquiring 
Coal for your earlier ships are now over.
Civilopedia entry
The term “cruiser” was first used in the mid-17th Century AD to refer to a warship that could operate independently of a fleet – fast enough to run away from anything with bigger guns and big enough to blast apart anything with smaller ones. During the next couple centuries these were often commerce raiders, and occasionally used in fleet actions to screen the main body. So they didn’t figure prominently in naval affairs ... until the advent of long-range missiles. While a number of navies invested in the design and construction of missile cruisers during the Cold War (even the mighty Peruvian navy had one), only the Americans and Soviets have kept theirs afloat. The first of the U.S. Navy’s Ticonderoga-class cruisers was launched in 1981, arguably the most powerful vessels still in service, armed with 122 launch tubes with a staggering variety of surface-to-surface, surface-to-air, and anti-submarine missiles, thus able to kill just about anything.
Trivia
- Interestingly, rather than an actual missile cruiser, the model used for the Missile Cruiser in Civilization VI is that of an old Soviet Nanuchka-class corvette. This has proven to be somewhat controversial among players.
See also
- Missile Cruiser in other Civilization games