Salamanca is the Iroquois capital in Civilization III and an Iroquois and Spanish city in other Civilization and Call to Power games and C-evo. In real life, it refers to the following places:
- Salamanca, Spain is the capital of the Province of Salamanca in the autonomous community of Castile and León in present-day Spain.
- Salamanca, New York is a city in Cattaraugus County, New York, United States, inside the Allegany Indian Reservation, one of two governed by the Seneca Nation of New York (which is one of the six tribes of the Iroquois Confederacy).
In scenarios, it may appear as a Castilian city in Middle Ages.