Syracuse is an American, Greek, Iroquois, and Roman city in the Civilization and Call to Power games and C-evo. In real life, it refers to the following places:
- Syracuse, Sicily is a city in Sicily, present-day Italy.
- Syracuse, New York is a city in present-day New York, USA.
In scenarios, it may appear as a Carthaginian, Macedonian, Vandal, or Western Roman city.